Two pronged approach
Achieving optimal IAQ requires two HVAC system functions and/or components: filtration and ventilation, and the provision of fresh air.
Filtration and the addition of a treatment system like UV lights can have a big impact, but they have their limitations. MERV (minimum efficiency reporting value) 13 filters have become the gold standard for indoor air filtration. According to the National Air Filter Association, a MERV-13 filter is able to remove 90 percent of particles between 3 and 10 microns in size, 85 percent of particles between 1 and 3 microns in size, and 50 percent of particles between 0.30 and 1 micron in size.
The COVID-19 virus measures between .1 and .5 microns, but is generally attached to other particles in an airstream, such as water vapor (moisture). These COVID-laden particles range between .5 and 1.0 microns in size. MERV 13 filtration is an important part of the equation, but it is not the end all be all.
The second part of the healthy air equation is ventilation, or the introduction of outside air. Increasing the amount of fresh air decreases the concentration of airborne particles within an occupied space. This becomes more effective than filtration alone.
To help combat COVID, ASHRAE has recommended maintaining air circulation 24 hours a day, instead of shutting systems down when unoccupied. Another method of scrubbing the air in a building includes purging its air volume for several hours before occupation and again after close of business.
Yes, this is energy intensive. Not only is continual operation of system fan motors a consideration, but the greater the disparity between outdoor ambient temperatures and indoor setpoint, the more taxing it is to condition fresh air.
So, can we have our cake and eat it, too?